Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962816 | 1.00 | L3MBTL1 (0.38) | L3MBTL1EPHX2KDM1ARCOR1DHODH | |
| SCHEMBL8962707 | 0.96 | L3MBTL1 (0.41) | L3MBTL1EPHX2KDM1ARCOR1DHODH | |
| SCHEMBL8962715 | 0.96 | L3MBTL1 (0.41) | L3MBTL1EPHX2KDM1ARCOR1DHODH | |
| SCHEMBL8963027 | 0.96 | MEN1 (0.36) | L3MBTL1EPHX2KDM1ARCOR1DHODH | |
| SCHEMBL8963060 | 0.93 | EPHX2 (0.37) | L3MBTL1EPHX2KDM1ARCOR1DHODH | |
| SCHEMBL8963064 | 0.93 | EPHX2 (0.37) | L3MBTL1EPHX2KDM1ARCOR1DHODH | |
| SCHEMBL2741560 | 0.84 | L3MBTL1 (0.40) | L3MBTL1EPHX2KDM1ARCOR1DHODH | |
| SCHEMBL4564168 | 0.83 | L3MBTL1 (0.47) | L3MBTL1EPHX2KDM1ARCOR1DHODH | |
| SCHEMBL8963019 | 0.82 | HDAC2 (0.45) | HTR2CHDAC2 | |
| SCHEMBL8963014 | 0.82 | HDAC2 (0.45) | HTR2CHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |