Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963060 | 1.00 | EPHX2 (0.37) | EPHX2ESR2KDM1ARCOR1GRM2 | |
| SCHEMBL8962828 | 0.93 | L3MBTL1 (0.38) | EPHX2KDM1ARCOR1GRM2L3MBTL1 | |
| SCHEMBL8962816 | 0.93 | L3MBTL1 (0.38) | EPHX2KDM1ARCOR1GRM2L3MBTL1 | |
| SCHEMBL8963027 | 0.89 | MEN1 (0.36) | EPHX2KDM1ARCOR1GRM2L3MBTL1 | |
| SCHEMBL8962707 | 0.89 | L3MBTL1 (0.41) | EPHX2KDM1ARCOR1GRM2L3MBTL1 | |
| SCHEMBL8962715 | 0.89 | L3MBTL1 (0.41) | EPHX2KDM1ARCOR1GRM2L3MBTL1 | |
| SCHEMBL8963125 | 0.84 | DRD2 (0.43) | ESR2GRM2ESR1CYP3A4CYP2C9 | |
| SCHEMBL8963134 | 0.84 | DRD2 (0.43) | ESR2GRM2ESR1CYP3A4CYP2C9 | |
| SCHEMBL8458133 | 0.84 | ESR2 (0.34) | EPHX2ESR2KDM1ARCOR1GRM2 | |
| SCHEMBL8458130 | 0.84 | ESR2 (0.34) | EPHX2ESR2KDM1ARCOR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |