Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962715 | 1.00 | L3MBTL1 (0.41) | L3MBTL1P2RY14SCN10AEPHX2S1PR1 | |
| SCHEMBL8962816 | 0.96 | L3MBTL1 (0.38) | L3MBTL1EPHX2GRM2KDM1ARCOR1 | |
| SCHEMBL8962828 | 0.96 | L3MBTL1 (0.38) | L3MBTL1EPHX2GRM2KDM1ARCOR1 | |
| SCHEMBL8963027 | 0.92 | MEN1 (0.36) | L3MBTL1P2RY14EPHX2GRM2KDM1A | |
| SCHEMBL8963064 | 0.89 | EPHX2 (0.37) | L3MBTL1EPHX2GRM2KDM1ARCOR1 | |
| SCHEMBL8963060 | 0.89 | EPHX2 (0.37) | L3MBTL1EPHX2GRM2KDM1ARCOR1 | |
| SCHEMBL8963179 | 0.82 | CTSK (0.37) | EPHX2S1PR1GRIN2BGRM2DHODH | |
| SCHEMBL8963176 | 0.82 | CTSK (0.37) | EPHX2S1PR1GRIN2BGRM2DHODH | |
| SCHEMBL8962900 | 0.81 | HTR2C (0.53) | P2RY14KIF11KDM1A | |
| SCHEMBL8963003 | 0.81 | DRD2 (0.42) | KDM1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |