Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962830 | 0.96 | KDM1A (0.47) | KDM1ACYP11B1CYP11B2RXRAGRIN1 | |
| SCHEMBL8962822 | 0.96 | KDM1A (0.47) | KDM1ACYP11B1CYP11B2RXRAGRIN1 | |
| SCHEMBL8963103 | 0.86 | KIF11 (0.46) | KDM1ACYP11B1CYP11B2KIF11 | |
| SCHEMBL8963089 | 0.86 | KIF11 (0.46) | KDM1ACYP11B1CYP11B2KIF11 | |
| SCHEMBL9543549 | 0.86 | KDM1A (0.39) | KDM1ACYP11B1CYP11B2RXRAGRIN1 | |
| SCHEMBL13002924 | 0.85 | KDM1A (0.47) | KDM1ACYP11B1CYP11B2CHRM2DRD2 | |
| SCHEMBL8962654 | 0.85 | KDM1A (0.34) | KDM1AHTR2AHTR2C | |
| SCHEMBL8835135 | 0.85 | KDM1A (0.42) | KDM1ACYP11B1CYP11B2CHRM2DRD2 | |
| SCHEMBL8835133 | 0.85 | KDM1A (0.42) | KDM1ACYP11B1CYP11B2CHRM2DRD2 | |
| SCHEMBL8835219 | 0.85 | KDM1A (0.42) | KDM1ACYP11B1CYP11B2CHRM2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |