Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 8/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963177 | 1.00 | SPHK1 (0.37) | SPHK1RARBSPHK2NPC1MAPT | |
| SCHEMBL8962762 | 0.96 | NFKB1 (0.33) | SPHK1RARBNPC1MAPTRAB9A | |
| SCHEMBL8962758 | 0.96 | NFKB1 (0.33) | SPHK1RARBNPC1MAPTRAB9A | |
| SCHEMBL8963187 | 0.90 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL8963185 | 0.90 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL8962857 | 0.87 | SPHK1 (0.40) | SPHK1RARBSPHK2NPC1MAPT | |
| SCHEMBL8962934 | 0.84 | PDE8B (0.31) | — | |
| SCHEMBL8962927 | 0.84 | PDE8B (0.31) | — | |
| SCHEMBL8963259 | 0.83 | RARB (0.36) | SPHK1RARBSPHK2NPC1MAPT | |
| SCHEMBL8963141 | 0.83 | RAB9A (0.41) | SPHK1SPHK2NPC1MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |