Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323307 | 0.89 | NPC1 (0.36) | NPC1RAB9AEPHX1MEN1KMT2A | |
| SCHEMBL18486592 | 0.86 | NPC1 (0.46) | NPC1RAB9AEPHX1LMNAALOX12 | |
| SCHEMBL9172166 | 0.77 | POLL (0.40) | MEN1KMT2ATSHRHTR2C | |
| SCHEMBL24782558 | 0.76 | NPC1 (0.39) | NPC1RAB9AEPHX1LMNAMEN1 | |
| SCHEMBL17754463 | 0.74 | OPRM1 (0.32) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL18486486 | 0.74 | NPC1 (0.32) | NPC1RAB9ALMNATAS1R3TAS1R1 | |
| SCHEMBL9177763 | 0.73 | POLL (0.40) | MEN1KMT2AHTR2C | |
| SCHEMBL5569714 | 0.73 | MEN1 (0.38) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL14747871 | 0.72 | NPC1 (0.44) | NPC1RAB9AEPHX1LMNAMEN1 | |
| SCHEMBL22156237 | 0.71 | MAPT (0.37) | NPC1RAB9ALMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511558-B1 | Process for the resolution of racemates and associates of diastereoisomers | HOFFMANN LA ROCHE (CH) | 1996-10-23 | — | — | EP | claimed |
| EP-0408340-B1 | Ruthenium-optically active phoshine complex useful as catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| EP-0408338-B1 | Catalytic production of carboxylic acids and esters thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5334766-A | Process for the resolution of racemic diphosphine oxides | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |
| US-5087728-A | Hydrogenating unsaturated compound using rhodium or ruthenium complex catalyst with specific diphosphine ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-02-11 | — | — | US | disclosed |
| US-5021593-A | Used as hydrogenation, silylation or isomerization catalysts | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0408340-A2 | Ruthenium-optically active phoshine complex useful as catalyst | Takasago International Corporation (JP) | 1991-01-16 | — | — | EP | disclosed |
| EP-0408338-A2 | Catalytic production of carboxylic acids and esters thereof | Takasago International Corporation (JP) | 1991-01-16 | — | — | EP | disclosed |
| EP-0408338-A2 | Catalytic production of carboxylic acids and esters thereof | Takasago International Corporation (JP) | 1991-01-16 | — | — | EP | disclosed |