Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | TCF4 | P15884 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691086 | 0.96 | HTR7 (0.41) | MEN1KMT2ATOP1HPGDALDH1A1 | |
| SCHEMBL30318774 | 0.96 | HTR7 (0.41) | MEN1KMT2ATOP1HPGDALDH1A1 | |
| SCHEMBL9172166 | 0.89 | POLL (0.40) | MEN1KMT2ATOP1HPGDALDH1A1 | |
| SCHEMBL29559258 | 0.87 | HPGD (0.41) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9177763 | 0.86 | POLL (0.40) | MEN1KMT2ATOP1HPGDALDH1A1 | |
| SCHEMBL20718751 | 0.82 | CA1 (0.40) | HPGDALDH1A1SMN1; SMN2GPR84NPC1 | |
| SCHEMBL31470225 | 0.77 | GPR84 (0.44) | MEN1KMT2ATOP1HPGDALDH1A1 | |
| SCHEMBL28167753 | 0.77 | GPR84 (0.44) | MEN1KMT2ATOP1HPGDALDH1A1 | |
| SCHEMBL30008143 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30106495 | 0.76 | MEN1 (0.38) | MEN1KMT2ATOP1SMN1; SMN2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761549-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006002730-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2006-01-12 | — | — | WO | disclosed |