SCHEMBL8963330

SCHEMBL8963330

Cc1cc(Cc2ccc(C#N)c(C)c2)ccc1C#N

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
TSHR P16473 1/20 0.46
NOS3 P29474 2/20 0.43
NOS1 P29475 2/20 0.43
SNCA P37840 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.39
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.38
MAOB P27338 4/20 0.37
TRPV4 Q9HBA0 1/20 0.36
DPP4 P27487 1/20 0.36
KCNH2 Q12809 1/20 0.36
MAOA P21397 2/20 0.36
CACNA1H O95180 2/20 0.36
EGLN2 Q96KS0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17971119 0.89 TRPV4 (0.42) ESR1ESR2TSHRNOS3NOS1
SCHEMBL20017753 0.86 LOXL2 (0.52) ESR1ESR2TSHRNOS3NOS1
SCHEMBL12763837 0.85 CYP2A6 (0.48) TSHRNOS3NOS1MRGPRX4MAOB
SCHEMBL28248401 0.83 NOS3 (0.47) TSHRNOS3NOS1MRGPRX4MAOB
SCHEMBL536160 0.83 TSHR (0.43) ESR1ESR2TSHRNOS3NOS1
SCHEMBL25786460 0.83 TSHR (0.43) TSHRNOS3NOS1MRGPRX4MAOB
SCHEMBL8226653 0.83 LOXL2 (0.47) TSHRNOS3NOS1MRGPRX4LOXL2
SCHEMBL2546677 0.83 TSHR (0.43) TSHRNOS3NOS1MRGPRX4PDE3B
SCHEMBL12113905 0.83 TSHR (0.46) ESR1ESR2TSHRSNCAPDE3B
SCHEMBL24528788 0.82 NOS3 (0.46) TSHRNOS3NOS1MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106511-A Power module manufacturing method and power module 信越化学工业株式会社 2022-03-01 CN disclosed
CN-104851826-B Vacuum laminating apparatus and method for manufacturing semiconductor device 信越化学工业株式会社 2020-02-21 CN disclosed
US-5488144-A Bifunctional aromatic cyanates, prepolymers and electrical laminates made therefrom KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-30 US disclosed