Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184723 | 0.82 | ALDH1A1 (0.62) | NPBWR1ALDH1A1HTTHSD17B10PTGS2 | |
| SCHEMBL4047300 | 0.78 | ALDH1A1 (0.54) | NPBWR1ALDH1A1HTTHSD17B10PTGS2 | |
| Benzyl Bromide SCHEMBL7816396 | 0.73 | ALDH1A1 (0.49) | NPBWR1ALDH1A1HTTHSD17B10PTGS2 | |
| SCHEMBL6604659 | 0.70 | PFKFB3 (0.52) | NPBWR1ALDH1A1HTTHSD17B10PTGS2 | |
| SCHEMBL4383612 | 0.70 | NPBWR1 (0.75) | NPBWR1ALDH1A1HTTHSD17B10NPSR1 | |
| SCHEMBL23535857 | 0.69 | NPBWR1 (0.67) | NPBWR1PKM | |
| SCHEMBL4178254 | 0.69 | ALDH1A1 (0.61) | NPBWR1ALDH1A1HTTHSD17B10NPSR1 | |
| SCHEMBL6232624 | 0.69 | MAPK14 (0.67) | NPBWR1ALDH1A1HTTHSD17B10NR2E3 | |
| SCHEMBL6378489 | 0.69 | NPBWR1 (0.54) | NPBWR1ALDH1A1HTTHSD17B10PTGS2 | |
| SCHEMBL17397366 | 0.68 | TSHR (0.56) | ALDH1A1HTTHSD17B10NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8198855-A | — | — | None | — | — | JP | disclosed |
| JP-H08198855-A | PYRIDAZINONE DERIVATIVE AND VERMIN CONTROLLING AGENT | NISSAN CHEM IND LTD | 1996-08-06 | — | — | JP | disclosed |