Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963651 | 0.94 | CCNT1 (0.32) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL8963596 | 0.94 | CCNT1 (0.32) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL8963978 | 0.94 | NAAA (0.30) | PDE5AHDAC1HDAC6NAAA | |
| SCHEMBL12999813 | 0.94 | MMP2 (0.30) | MMP2MMP3 | |
| SCHEMBL8965452 | 0.94 | NAAA (0.33) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL8964186 | 0.93 | RARB (0.30) | PDE5AHDAC1HDAC6NAAA | |
| SCHEMBL8963693 | 0.93 | PPARD (0.32) | — | |
| SCHEMBL8963542 | 0.93 | CCNT1 (0.32) | NAAAMMP2MMP3GRIN1GRIN2B | |
| SCHEMBL8963829 | 0.92 | RARB (0.32) | — | |
| SCHEMBL8963818 | 0.92 | RARB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |