Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 8/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963679 | 0.76 | MEN1 (0.42) | PIN1OPRD1PRMT5MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8963658 | 0.75 | MEN1 (0.39) | PIN1OPRD1PRMT5MAPTMEN1 | |
| SCHEMBL8964151 | 0.73 | PIN1 (0.71) | PIN1SLC9A1MAPTCYP1A2MAPK1 | |
| SCHEMBL8963580 | 0.71 | PRMT5 (0.40) | OPRD1PRMT5MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.70 | PRMT5 (0.40) | OPRD1PRMT5MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8963905 | 0.70 | PIN1 (0.36) | PIN1OPRD1PRMT5MAPTMEN1 | |
| SCHEMBL11564100 | 0.70 | PIN1 (0.81) | PIN1SLC9A1MAPTCYP1A2MAPK1 | |
| SCHEMBL316552 | 0.70 | PIN1 (1.00) | PIN1SLC9A1MAPTCYP1A2MAPK1 | |
| SCHEMBL8963723 | 0.70 | PIN1 (0.51) | PIN1SLC9A1MEN1KMT2A | |
| SCHEMBL8963650 | 0.70 | CHEK2 (0.40) | OPRD1PRMT5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |