Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8963783 | 0.99 | PRMT5 (0.40) | PRMT5MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8963679 | 0.94 | MEN1 (0.42) | PRMT5MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8964088 | 0.94 | OPRD1 (0.37) | PRMT5MEN1KMT2AOPRD1TNKS | |
| SCHEMBL8963650 | 0.91 | CHEK2 (0.40) | PRMT5MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8963675 | 0.90 | TACR1 (0.36) | PRMT5MEN1KMT2AOPRD1TNKS | |
| SCHEMBL8963817 | 0.90 | PRMT5 (0.42) | PRMT5MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8963467 | 0.89 | OPRD1 (0.41) | PRMT5MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8964068 | 0.89 | PRMT5 (0.44) | PRMT5MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8963516 | 0.89 | CHEK2 (0.42) | PRMT5OPRD1 | |
| SCHEMBL8963637 | 0.89 | MAPK13 (0.37) | PRMT5SLC6A4SLC6A2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | claimed |
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |