Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963580 | 0.94 | PRMT5 (0.40) | MEN1KMT2APRMT5DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.93 | PRMT5 (0.40) | MEN1KMT2APRMT5DRD2DRD4 | |
| SCHEMBL8963650 | 0.92 | CHEK2 (0.40) | MEN1KMT2APRMT5DRD2DRD4 | |
| SCHEMBL8963979 | 0.92 | CYP2D6 (0.42) | MEN1KMT2APRMT5DRD2DRD4 | |
| SCHEMBL8963860 | 0.91 | PIN1 (0.43) | MEN1KMT2APRMT5SLC6A4SLC6A2 | |
| SCHEMBL8964068 | 0.90 | PRMT5 (0.44) | MEN1KMT2APRMT5SLC6A4SLC6A2 | |
| SCHEMBL8963467 | 0.90 | OPRD1 (0.41) | MEN1KMT2APRMT5SLC6A4SLC6A2 | |
| SCHEMBL8963787 | 0.89 | PIN1 (0.45) | MEN1KMT2ASLC6A4SLC6A2PIN1 | |
| SCHEMBL8964088 | 0.88 | OPRD1 (0.37) | MEN1KMT2APRMT5DRD2DRD4 | |
| SCHEMBL8964174 | 0.88 | TACR1 (0.38) | MEN1KMT2APRMT5DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |