Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963517 | 0.82 | DRD2 (0.49) | DRD2DRD4DRD3GNRHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL8963906 | 0.77 | PIN1 (0.34) | NPY5RMAPTDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL8964006 | 0.75 | DRD2 (0.34) | NPY5RMAPTDRD2DRD4DRD3 | |
| SCHEMBL8963527 | 0.72 | PRMT5 (0.32) | DRD2DRD4DRD3TRPV1TNKS | |
| Hydrochloric Acid SCHEMBL8964045 | 0.72 | MEN1 (0.39) | MAPTDRD2DRD4DRD3 | |
| SCHEMBL8963694 | 0.69 | TRPV1 (0.37) | TRPV1GNRHR | |
| SCHEMBL8963847 | 0.69 | DRD2 (0.53) | DRD2DRD4DRD3CYP3A4CYP2C9 | |
| SCHEMBL8963984 | 0.67 | DRD2 (0.51) | DRD2DRD4DRD3CYP3A4CYP2C9 | |
| SCHEMBL8963495 | 0.67 | DRD2 (0.50) | MAPTDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL8963742 | 0.67 | MEN1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |