Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.37 |
| ▸ | GNRHR | P30968 | 10/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964228 | 0.90 | TP53 (0.36) | KIT | |
| SCHEMBL8963673 | 0.71 | GNRHR (0.46) | GNRHROPRD1OPRK1 | |
| SCHEMBL8963977 | 0.69 | NPY5R (0.35) | TRPV1GNRHR | |
| SCHEMBL8963691 | 0.67 | TACR1 (0.34) | GNRHROPRD1HDAC6 | |
| SCHEMBL8963753 | 0.67 | ADRA2A (0.43) | — | |
| Hydrochloric Acid SCHEMBL8963865 | 0.65 | OPRD1 (0.38) | OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL8964047 | 0.64 | OPRD1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8963706 | 0.63 | LIMK2 (0.39) | OPRM1OPRD1OPRK1LIMK2 | |
| SCHEMBL8964029 | 0.63 | DRD4 (0.44) | HRH2 | |
| Hydrochloric Acid SCHEMBL8963554 | 0.61 | MEN1 (0.44) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |