Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963753 | 0.82 | ADRA2A (0.43) | DRD4DRD2DRD3MAPTNPY5R | |
| SCHEMBL25154269 | 0.73 | DRD4 (0.53) | DRD4GSK3BMAPTHRH2 | |
| SCHEMBL15936456 | 0.72 | SMO (0.63) | MAPK1MAPT | |
| SCHEMBL15936392 | 0.70 | SMO (0.65) | MAPK1MAPT | |
| SCHEMBL8964019 | 0.68 | DRD2 (0.71) | DRD4DRD2DRD3USP2TP53 | |
| SCHEMBL27979641 | 0.68 | MAPT (0.68) | MAPTHRH2 | |
| SCHEMBL6741206 | 0.68 | MAPT (0.68) | MAPTHRH2 | |
| SCHEMBL4048121 | 0.68 | MAPT (0.68) | MAPTHRH2 | |
| SCHEMBL20284487 | 0.67 | HRH2 (0.66) | MAPTHRH2 | |
| SCHEMBL14528083 | 0.67 | HRH2 (0.66) | MAPTHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |