Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93243 | 0.77 | CA1 (0.54) | ALDH1A1KMT2AADRA2BHTTSLC6A2 | |
| SCHEMBL4654255 | 0.76 | DRD1 (0.48) | DRD1ALDH1A1NR1I2KDM4EGAA | |
| SCHEMBL1698265 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EHTR1ASLC6A2SLC6A3 | |
| SCHEMBL19527662 | 0.73 | PDE4D (0.43) | DRD1ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL28355135 | 0.72 | HRH1 (0.47) | ALDH1A1KDM4ESMN1; SMN2ADRA2AADRA2B | |
| SCHEMBL7806133 | 0.72 | SLC6A4 (0.42) | KDM4ESMN1; SMN2HTR1AHTTSLC6A2 | |
| SCHEMBL20064142 | 0.70 | PDE4B (0.47) | DRD1KDM4EKMT2AHTR1AADRA2A | |
| SCHEMBL28693925 | 0.70 | LMNA (0.33) | ALDH1A1KDM4ELMNA | |
| SCHEMBL23813151 | 0.70 | ALDH1A1 (0.48) | DRD1ALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL9527314 | 0.70 | CA1 (0.62) | ALDH1A1KDM4EGAAKMT2AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695293-A1 | 10,11-METHANODIBENZOSUBERANE DERIVATIVES USED AS CHEMOSENSITIZING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024107-A1 | 10,11-METHANODIBENZOSUBERANE DERIVATIVES USED AS CHEMOSENSITIZING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1994-10-27 | — | — | WO | disclosed |