Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL11358614 | 0.93 | ALDH1A1 (0.47) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| Carbon Monoxide SCHEMBL10727014 | 0.93 | ALDH1A1 (0.47) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| Carbon Monoxide SCHEMBL11358613 | 0.91 | ALDH1A1 (0.46) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL17346039 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1931125 | 0.78 | ALDH1A1 (0.78) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL35092 | 0.78 | CYP3A4 (0.45) | ALDH1A1CYP3A4KDM4E | |
| SCHEMBL29179 | 0.78 | CYP3A4 (0.45) | ALDH1A1CYP3A4KDM4E | |
| SCHEMBL420011 | 0.78 | ALDH1A1 (0.78) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8964297 | 0.78 | KCNH3 (0.36) | ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL2945616 | 0.76 | MEN1 (0.44) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343734-A1 | Catalyst compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-11-29 | — | — | EP | claimed |
| JP-2020522-A | — | — | None | — | — | JP | disclosed |
| EP-0357101-B1 | Copolymers of carbon monoxide | SHELL INT RESEARCH (NL) | 1996-02-28 | — | — | EP | disclosed |
| EP-0343734-B1 | CATALYST COMPOSITIONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-11 | — | — | EP | disclosed |
| EP-0349084-B1 | POLYKETONE DERIVED PRODUCTS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-05-05 | — | — | EP | disclosed |
| US-4948870-A | Polymerization process | SHELL OIL COMPANY (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0357101-A2 | Copolymers of carbon monoxide | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-03-07 | — | — | EP | disclosed |
| JP-H0220522-A | CATALYST COMPOSITION | SHELL INTERNATL RES MAATSCHAPPIJ BV | 1990-01-24 | — | — | JP | disclosed |
| EP-0349084-A2 | Polyketone derived products | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-01-03 | — | — | EP | disclosed |
| EP-0343734-A1 | Catalyst compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-11-29 | — | — | EP | disclosed |