SCHEMBL8964297

SCHEMBL8964297

CSCCCP(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 1/20 0.36
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8735569 0.87 CYP3A4 (0.36) KCNH3CYP3A4TDP1ALDH1A1MAPK1
SCHEMBL5694888 0.80 TSHR (0.35) CYP3A4TDP1
SCHEMBL29179 0.79 CYP3A4 (0.45) CYP3A4TDP1ALDH1A1
SCHEMBL35092 0.79 CYP3A4 (0.45) CYP3A4TDP1ALDH1A1
SCHEMBL7927952 0.78 CYP3A4 (0.39) CYP3A4TDP1
Propane SCHEMBL17007613 0.78 TDP1 (0.39) CYP3A4TDP1
SCHEMBL8964236 0.78 ALDH1A1 (0.54) CYP3A4ALDH1A1MAPK1
SCHEMBL17345935 0.77 MAPT (0.30)
SCHEMBL7934432 0.77 CYP3A4 (0.43) CYP3A4TDP1
SCHEMBL954340 0.77 CYP3A4 (0.43) CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0343734-A1 Catalyst compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-11-29 EP claimed
EP-0357101-B1 Copolymers of carbon monoxide SHELL INT RESEARCH (NL) 1996-02-28 EP disclosed
EP-0343734-B1 CATALYST COMPOSITIONS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-08-11 EP disclosed
EP-0349084-B1 POLYKETONE DERIVED PRODUCTS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-05-05 EP disclosed
US-4948870-A Polymerization process SHELL OIL COMPANY (US) 1990-08-14 US disclosed
EP-0357101-A2 Copolymers of carbon monoxide SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-03-07 EP disclosed
EP-0349084-A2 Polyketone derived products SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-01-03 EP disclosed
EP-0343734-A1 Catalyst compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-11-29 EP disclosed
US-4687874-A Selective hydroformylation process using alkyl diaryl phosphine rhodium carbonyl hydride catalysts EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-08-18 US disclosed
US-4687866-A Ligand exchange process for producing alkyl diaryl phosphine rhodium carbonyl hydrides EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-08-18 US disclosed
US-4668809-A ALKYL DIARYLPHOSPHINE RHODIUM CARBONYL HYDRIDES, HYDROFORMYLATION, OLEFINS EXXON RESEARCH AND ENGINEERING (US) 1987-05-26 US disclosed
US-4595753-A Nitrogen heterocycle substituted EXXON RESEARCH AND ENGINEERING CO. (US) 1986-06-17 US disclosed
EP-0024091-B1 HYDROFORMYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-04-03 EP disclosed
EP-0024091-A4 HYDROFORMYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS. EXXON RESEARCH ENGINEERING CO (US) 1981-07-16 EP disclosed
EP-0024091-A1 HYDROFORMYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS. EXXON RESEARCH ENGINEERING CO (US) 1981-02-25 EP disclosed
WO-1980001690-A1 CARBONYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS EXXON RESEARCH ENGINEERING CO (US) 1980-08-21 WO disclosed