Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propachlor SCHEMBL1701162 | 0.85 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2LMNATP53NPC1 | |
| Propachlor SCHEMBL65571 | 0.85 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2LMNATP53NPC1 | |
| SCHEMBL8963022 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL8963032 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL9869949 | 0.76 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2LMNATP53NPC1 | |
| SCHEMBL9869948 | 0.76 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2LMNATP53NPC1 | |
| SCHEMBL11653644 | 0.76 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2LMNATP53NPC1 | |
| SCHEMBL23804125 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| Propachlor SCHEMBL27354235 | 0.74 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2LMNATP53NPC1 | |
| SCHEMBL26088237 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNATP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578470-A | USING CYSTEINE | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST (NL) | 1996-11-26 | — | — | US | disclosed |