Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4981183 | 0.81 | FFAR3 (0.35) | FFAR3LCKFYNKDM4ETHRB | |
| SCHEMBL6970706 | 0.69 | FFAR3 (0.35) | FFAR3LCKFYNKDM4ETHRB | |
| SCHEMBL42490 | 0.67 | — | — | |
| SCHEMBL7525656 | 0.67 | CYP2D6 (0.41) | KDM4ETHRBRECQLCYP2D6CYP2C19 | |
| SCHEMBL28719441 | 0.67 | CYP2D6 (0.41) | THRBRECQLCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL1696899 | 0.67 | — | — | |
| SCHEMBL28657159 | 0.67 | KDM4E (0.41) | FFAR3LCKFYNKDM4ETHRB | |
| SCHEMBL15740599 | 0.67 | — | — | |
| SCHEMBL3743107 | 0.67 | — | — | |
| SCHEMBL43654 | 0.65 | ALDH1A1 (0.38) | THRBRECQLCYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969549-B2 | Antioxidant small molecules aimed at targeting metal-based oxidative stress in neurogenerative disorders | TEXAS CHRISTIAN UNIVERSITY (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140206862-A1 | Antioxidant Small Molecules Aimed at Targeting Metal-Based Oxidative Stress in Neurogenerative Disorders | TEXAS CHRISTIAN UNIVERSITY (US) | 2014-07-24 | — | — | US | disclosed |
| WO-2014113624-A1 | ANTIOXIDANT SMALL MOLECULES AIMED AT TARGETING METAL-BASED OXIDATIVE STRESS IN NEURODEGNERATIVE DISORDERS | TEXAS CHRISTIAN UNIVERSITY (US) | 2014-07-24 | — | — | WO | disclosed |
| US-5548060-A | ALKYLSULFONATION WITH A SULTONE | PENN STATE RESEARCH FOUNDATION, INC. (US) | 1996-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206862-A1 | Antioxidant Small Molecules Aimed at Targeting Metal-Based Oxidative Stress in Neurogenerative Disorders | PYCR1, PRNP, NLN | FFAR3 3148/4885LCK 4048/4885FYN 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.