SCHEMBL43654

SCHEMBL43654

O=C(O)NC(NC(=O)O)NC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
LDHA P00338 1/20 0.31
SRR Q9GZT4 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28657159 0.84 KDM4E (0.41) ALDH1A1THRBRECQLCYP2D6CYP2C19
SCHEMBL8754570 0.72
SCHEMBL42490 0.69
SCHEMBL5933862 0.69
SCHEMBL612192 0.69
SCHEMBL24042401 0.69 ALDH1A1 (0.41) ALDH1A1THRBRECQLCYP2C19
SCHEMBL7525656 0.69 CYP2D6 (0.41) ALDH1A1THRBRECQLCYP2D6CYP2C19
SCHEMBL968334 0.69
SCHEMBL28719441 0.69 CYP2D6 (0.41) ALDH1A1THRBRECQLCYP2D6CYP2C19
Bromide SCHEMBL11752199 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210246271-A1 POLYMERIC STABILIZING FORMULATIONS NANO PRECISION MEDICAL, INC. (US) 2021-08-12 US claimed
US-11021576-B2 Polymeric stabilizing formulations NANO PRECISION MEDICAL, INC. (US) 2021-06-01 US claimed
US-20200040140-A1 POLYMERIC STABILIZING FORMULATIONS NANO PRECISION MEDICAL, INC. (US) 2020-02-06 US claimed
US-10479868-B2 Polymeric stabilizing formulations NANO PRECISION MEDICAL, INC. (US) 2019-11-19 US claimed
US-20170274089-A1 POLYMERIC STABILIZING FORMULATIONS NANO PRECISION MEDICAL, INC. 2017-09-28 US claimed
WO-2017135893-A1 AQUEOUS DENDRITIC AMINE COATINGS NIPSEA TECHNOLOGIES PTE LTD (SG) 2017-08-10 WO claimed
WO-2016037128-A1 POLYMERIC STABILIZING FORMULATIONS NANO PRECISION MEDICAL, INC. (US) 2016-03-10 WO claimed
EP-2600844-A2 INTERIOR FUNCTIONALIZED HYPERBRANCHED DENDRON-CONJUGATED NANOPARTICLES AND USES THEREOF University Of Houston (US) 2013-06-12 EP claimed
WO-2012018383-A2 INTERIOR FUNCTIONALIZED HYPERBRANCHED DENDRON-CONJUGATED NANOPARTICLES AND USES THEREOF UNIVERSITY OF HOUSTON (US) 2012-02-09 WO claimed
US-20120029062-A1 Interior functionalized hyperbranched dendron-conjugated nanoparticles and uses thereof HOUSTON, UNIVERSITY OF 2012-02-02 US claimed
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 US claimed
US-7981444-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2011-07-19 US claimed
EP-2325236-A1 Dendritic polymers with enhanced amplification and interior functionality Dendritic Nanotechnologies Inc. (US) 2011-05-25 EP claimed
EP-1737899-A4 DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY DENDRITIC NANOTECHNOLOGIES INC (US) 2008-03-05 EP claimed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US claimed
US-20070244296-A1 Dendritic Polymers with Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-10-18 US claimed
EP-1737899-A2 DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY Dendritic Nanotechnologies, Inc. (US) 2007-01-03 EP claimed
WO-2006065266-A9 DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY DENDRITIC NANOTECHNOLOGIES INC (US) 2006-12-21 WO claimed
WO-2006065266-A2 DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY DENDRITIC NANOTECHNOLOGIES, INC. (US) 2006-06-22 WO claimed
US-5573757-A TOPICAL GEL ALLIANCE PHARMACEUTICAL CORP. (US) 1996-11-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170274089-A1 POLYMERIC STABILIZING FORMULATIONS IAPP, INSR, GPR119 ALDH1A1 2610/4885THRB 3948/4885RECQL 3481/4885
US-11021576-B2 Polymeric stabilizing formulations IAPP, INSR, GPR119 ALDH1A1 2610/4885THRB 3948/4885RECQL 3481/4885
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality MYD88, TLR3, TMEM97 ALDH1A1 2720/4885THRB 3966/4885RECQL 518/4885
US-10479868-B2 Polymeric stabilizing formulations IAPP, INSR, GPR119 ALDH1A1 2610/4885THRB 3948/4885RECQL 3481/4885
US-20200040140-A1 POLYMERIC STABILIZING FORMULATIONS IAPP, INSR, GPR119 ALDH1A1 2610/4885THRB 3948/4885RECQL 3481/4885
US-20210246271-A1 POLYMERIC STABILIZING FORMULATIONS VEGFA, CD44, CFTR ALDH1A1 3181/4885THRB 4811/4885RECQL 1032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.