Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964538 | 0.87 | MAPT (0.60) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL12368180 | 0.77 | MAPT (0.72) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6705537 | 0.76 | MAPT (1.00) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5126148 | 0.75 | MAPT (0.59) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8964804 | 0.74 | MAPT (0.51) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8964810 | 0.74 | ALDH1A1 (0.60) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22139803 | 0.74 | MEN1 (0.57) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5680962 | 0.74 | MAPT (0.92) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5017936 | 0.72 | PDE4B (0.57) | KCNMA1KDM4EHIF1AMAPTMEN1 | |
| SCHEMBL5022736 | 0.72 | MAPT (0.50) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |