Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 10/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13327368 | 0.82 | KCNMA1 (0.42) | MAPTALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL8964494 | 0.74 | KCNMA1 (0.64) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL8964538 | 0.74 | MAPT (0.60) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL13327385 | 0.74 | KCNMA1 (0.38) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8964873 | 0.69 | MAPT (0.39) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL12368180 | 0.69 | MAPT (0.72) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6705537 | 0.68 | MAPT (1.00) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11596339 | 0.67 | MAPT (0.63) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL22139803 | 0.66 | MEN1 (0.57) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL8964810 | 0.66 | ALDH1A1 (0.60) | MAPTALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |