Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964494 | 0.87 | KCNMA1 (0.64) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8964810 | 0.76 | ALDH1A1 (0.60) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12368180 | 0.76 | MAPT (0.72) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6705537 | 0.75 | MAPT (1.00) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8964804 | 0.74 | MAPT (0.51) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL22139803 | 0.73 | MEN1 (0.57) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5680962 | 0.73 | MAPT (0.92) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14363388 | 0.70 | ACLY (0.62) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5664848 | 0.70 | CA12 (0.65) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12127302 | 0.70 | MAPT (0.87) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |