Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964817 | 0.88 | L3MBTL1 (0.44) | ALDH1A1HPGDKDM4EPTPN7DUSP3 | |
| SCHEMBL11574320 | 0.78 | GRIN2D (0.47) | ALDH1A1HPGDKDM4EHSD17B10PTPN7 | |
| SCHEMBL3169791 | 0.74 | GPR3 (0.50) | ALDH1A1HPGDKDM4EPTPN7DUSP3 | |
| SCHEMBL8956112 | 0.74 | MAPT (0.52) | ALDH1A1HPGDKDM4ECDC25BL3MBTL1 | |
| Dibenzothiophene SCHEMBL30901453 | 0.73 | GPR3 (0.64) | ALDH1A1HPGDKDM4EL3MBTL1HTT | |
| Dibenzothiophene SCHEMBL29220086 | 0.73 | GPR3 (0.64) | ALDH1A1HPGDKDM4EL3MBTL1HTT | |
| SCHEMBL5017959 | 0.72 | CDC25B (0.50) | ALDH1A1HPGDKDM4EHSD17B10CDC25B | |
| SCHEMBL9507659 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL6850372 | 0.72 | KDM4E (0.52) | ALDH1A1HPGDKDM4EHSD17B10CDC25B | |
| SCHEMBL21624244 | 0.72 | NPC1 (0.67) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |