Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17443143 | 0.79 | MAPK1 (0.44) | APEX1MAPK1HSD17B10ALOX15L3MBTL1 | |
| SCHEMBL12095383 | 0.79 | PTPRC (0.45) | APEX1PGRALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3291279 | 0.77 | APEX1 (0.41) | APEX1PGRHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL28826501 | 0.74 | ALDH1A1 (0.36) | PGRMAPK1HSD17B10ALDH1A1TP53 | |
| SCHEMBL28826509 | 0.74 | HSP90AA1 (0.45) | PGRMAPK1HSD17B10ALOX15ALDH1A1 | |
| SCHEMBL1617518 | 0.73 | APEX1 (0.53) | APEX1PGRMAPK1HSD17B10ALOX15 | |
| SCHEMBL29370881 | 0.73 | APEX1 (0.53) | APEX1PGRMAPK1HSD17B10ALOX15 | |
| SCHEMBL9867937 | 0.73 | APEX1 (0.53) | APEX1PGRMAPK1HSD17B10ALOX15 | |
| SCHEMBL8965214 | 0.73 | PDK2 (0.49) | APEX1PGRMAPTPOLBESR2 | |
| SCHEMBL28482217 | 0.73 | TSHR (0.39) | APEX1PGRMAPK1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |