Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.64 |
| ▸ | KDM6A | O15550 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 6/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965506 | 0.88 | KDM4E (0.56) | KDM6BKDM6AMAPTALDH1A1HPGD | |
| SCHEMBL8964790 | 0.86 | RPS6KA3 (0.53) | KDM6BKDM6AMAPTALDH1A1HPGD | |
| SCHEMBL8964811 | 0.86 | KDM4E (0.56) | KDM6BKDM6AMAPTALDH1A1HPGD | |
| SCHEMBL8965508 | 0.86 | KDM6B (0.58) | KDM6BKDM6AMAPTALDH1A1HPGD | |
| SCHEMBL1296601 | 0.85 | KDM6B (0.78) | KDM6BKDM6AMAPTALDH1A1HPGD | |
| SCHEMBL8965198 | 0.85 | KDM6B (0.48) | KDM6BKDM6AMAPTALDH1A1HPGD | |
| SCHEMBL10725367 | 0.81 | KDM6B (0.71) | KDM6BKDM6AMAPTALDH1A1HPGD | |
| SCHEMBL1550613 | 0.79 | TOP2A (0.79) | KDM6BKDM6AMAPTALDH1A1HPGD | |
| SCHEMBL1550348 | 0.79 | TOP2A (0.79) | KDM6BKDM6AMAPTALDH1A1HPGD | |
| SCHEMBL29627559 | 0.78 | ALDH1A1 (0.65) | KDM6BKDM6AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | claimed |
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |