Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.58 |
| ▸ | KDM6A | O15550 | 1/20 | 0.58 |
| ▸ | TOP2A | P11388 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 9/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964800 | 0.86 | KDM6B (0.64) | KDM6BKDM6ATOP2AESR1ESR2 | |
| SCHEMBL29202874 | 0.86 | ALDH1A1 (0.54) | KDM6BKDM6ATOP2AESR1ESR2 | |
| SCHEMBL1296601 | 0.81 | KDM6B (0.78) | KDM6BKDM6ATOP2AESR1ESR2 | |
| SCHEMBL9603969 | 0.80 | ALDH1A1 (0.51) | KDM6BKDM6ATOP2AESR1ESR2 | |
| SCHEMBL9603965 | 0.80 | ALDH1A1 (0.51) | KDM6BKDM6ATOP2AESR1ESR2 | |
| SCHEMBL9603970 | 0.80 | ALDH1A1 (0.51) | KDM6BKDM6ATOP2AESR1ESR2 | |
| SCHEMBL9603976 | 0.79 | ALOX5 (0.51) | KDM6BKDM6ATOP2AESR1ESR2 | |
| SCHEMBL1550613 | 0.78 | TOP2A (0.79) | KDM6BKDM6ATOP2AESR1ESR2 | |
| SCHEMBL1550348 | 0.78 | TOP2A (0.79) | KDM6BKDM6ATOP2AESR1ESR2 | |
| SCHEMBL9603973 | 0.76 | KDM4E (0.54) | KDM6BKDM6ATOP2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |