Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 8/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM6A | O15550 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964752 | 0.83 | MAPT (0.35) | MAPTALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL13327367 | 0.83 | MAPT (0.43) | MAPTALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL13327377 | 0.77 | RAB9A (0.42) | MAPTALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL8964836 | 0.77 | CNR2 (0.31) | KDM4EESR1ESR2 | |
| SCHEMBL13327380 | 0.75 | RAB9A (0.38) | MAPTALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL13327369 | 0.74 | NPC1 (0.45) | MAPTALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL8964800 | 0.73 | KDM6B (0.64) | MAPTALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL3289127 | 0.73 | TP53 (0.30) | MAPTKDM4ESMN1; SMN2RAB9ATP53 | |
| SCHEMBL8965506 | 0.73 | KDM4E (0.56) | MAPTALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL8964790 | 0.72 | RPS6KA3 (0.53) | MAPTALDH1A1KDM4ESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | claimed |
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |