Sugi Predict

Sugi Predict / Compounds / SCHEMBL13327367

SCHEMBL13327367

SCHEMBL13327367

CCCC1(CCC)c2ccccc2-c2cc3nc(-c4ccc(-c5nc6cc7c(cc6o5)C(CCC)(CCC)c5ccccc5-7)c(O)c4)oc3cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.43
▸ SNCA P37840 1/20 0.43
▸ SMN1; SMN2 Q16637 4/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ NPC1 O15118 3/20 0.39
▸ RAB9A P51151 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ GAA P10253 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ HPGD P15428 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ ESR1 P03372 12/20 0.39
▸ ESR2 Q92731 12/20 0.39
▸ TP53 P04637 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13327377 0.90 RAB9A (0.42) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL13327380 0.88 RAB9A (0.38) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL13327369 0.87 NPC1 (0.45) MAPTKDM4ENPC1RAB9AALDH1A1
SCHEMBL8964873 0.83 MAPT (0.39) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL8964752 0.78 MAPT (0.35) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL29723524 0.78 KDM4E (0.49) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL3289965 0.78 KDM4E (0.49) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL3289127 0.75 TP53 (0.30) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL13360046 0.75 NPC1 (0.35) NPC1PTGS2HDAC6
SCHEMBL8964836 0.73 CNR2 (0.31) KDM4EESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713452-B2 Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2010-05-11 — — US disclosed
US-7713452-B2 Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2010-05-11 — — US disclosed
US-20080064880-A1 Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) 2008-03-13 — — US disclosed
US-20080064880-A1 Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) 2008-03-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064880-A1 Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them CRYAB, CRYAA, CRYZ MAPT 68/4885SNCA 3859/4885SMN1; SMN2 4736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.