Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | DAO | P14920 | 2/20 | 0.53 |
| ▸ | DDO | Q99489 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409436 | 0.88 | KDM4E (0.53) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| SCHEMBL19608948 | 0.88 | KDM4E (0.53) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| SCHEMBL9293419 | 0.84 | KDM4E (0.56) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| SCHEMBL11498132 | 0.82 | KDM4E (0.72) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| SCHEMBL374022 | 0.80 | RAB9A (0.74) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| SCHEMBL29631691 | 0.80 | RAB9A (0.74) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| 2-(2'-Hydroxyphenyl)-1H-Indole SCHEMBL6742396 | 0.78 | KDM4E (0.68) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| 2-(2'-Hydroxyphenyl)-1H-Indole SCHEMBL30486077 | 0.78 | KDM4E (0.68) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| SCHEMBL11792887 | 0.78 | KDM4E (0.71) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| SCHEMBL30579770 | 0.78 | KDM4E (0.71) | KDM4EMAPTHPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |
| US-5298189-A | Fluorescent compound dispersed in polymer matrix, no self-absorption, stable to high energy radiation | NANOPTICS INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |