Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671502 | 0.91 | TP53 (0.35) | TP53NOTUMF7F3DYRK1A | |
| SCHEMBL10469489 | 0.72 | MAPK13 (0.31) | DYRK1AAHRMAPK1 | |
| SCHEMBL8650493 | 0.71 | CYP2A6 (0.32) | ALDH1A1TDP1ALOX15CYP2A6AHR | |
| SCHEMBL10469300 | 0.71 | NQO2 (0.37) | TP53ALDH1A1CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL17664095 | 0.63 | TP53 (0.36) | TP53NOTUMF7F3DYRK1A | |
| SCHEMBL207169 | 0.62 | TP53 (0.35) | TP53F7F3DYRK1ATSHR | |
| SCHEMBL2327323 | 0.62 | TP53 (0.35) | TP53F7F3DYRK1ATSHR | |
| SCHEMBL1387779 | 0.62 | NQO2 (0.33) | — | |
| SCHEMBL14743082 | 0.62 | S100A4 (0.44) | TP53F7F3DYRK1ATSHR | |
| SCHEMBL209538 | 0.60 | TP53 (0.33) | TP53F7F3DYRK1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917576-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-12-08 | — | — | EP | claimed |
| WO-2020155017-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2020-08-06 | — | — | WO | claimed |
| EP-3621652-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | Hangzhou DAC Biotech Co, Ltd (CN) | 2020-03-18 | — | — | EP | claimed |
| US-5541193-A | ORGAN TRANSPLANTS | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | claimed |
| US-4010178-A | Carbonic acid esters, and the preparation thereof and their use | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-03-01 | — | — | US | claimed |
| JP-60013757-A | — | — | None | — | — | JP | disclosed |
| US-20240058478-A1 | FOLATE RECEPTOR-TARGETED CONJUGATES, COMPOSITIONS, AND DELIVERY TO THE CENTRAL NERVOUS SYSTEM | PURDUE RESEARCH FOUNDATION | 2024-02-22 | — | — | US | disclosed |
| CN-117337190-A | Folate receptor targeted conjugates, compositions and delivery to the central nervous system | 普渡研究基金会 | 2024-01-02 | — | — | CN | disclosed |
| US-20230331767-A1 | TARGETED STEROID COMPOUNDS | PURDUE RESEARCH FOUNDATION | 2023-10-19 | — | — | US | disclosed |
| CN-115003308-A | Targeted steroid compounds | 普渡研究基金会 | 2022-09-02 | — | — | CN | disclosed |
| EP-3917576-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| EP-3814358-A1 | METHOD FOR PREPARING 2-INDOLINOSPIRONE COMPOUND AND INTERMEDIATE THEREOF | Ascentage Pharma (Suzhou) Co., Ltd. (CN) | 2021-05-05 | — | — | EP | disclosed |
| US-5541193-A | ORGAN TRANSPLANTS | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| WO-1994021258-A1 | HETEROCYCLE-CONTAINING MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0279633-B1 | ANTICONVULSANT AGENTS | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| EP-0279633-A2 | Anticonvulsant agents | ELI LILLY AND COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |
| US-4604386-A | CONTROL OF GRAMPOSITIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0168222-A2 | 3-(Alkynylalkyloxy) Cephalosporins | ELI LILLY AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |
| JP-S6013757-A | AGENT FOR PRODUCING ACTIVE AMINO ACID ESTER | OGURA HARUO | 1985-01-24 | — | — | JP | disclosed |
| US-4242507-A | Sulfonic acid esters | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331767-A1 | TARGETED STEROID COMPOUNDS | CYP11B2, FOLR2, CYP11B1 | TP53 626/4885NOTUM 4446/4885F7 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.