Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 5/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965132 | 0.83 | BCL2L1 (0.48) | RELANFE2L2HDAC2HDAC8CYP3A4 | |
| SCHEMBL8965561 | 0.83 | BCL2L1 (0.48) | RELANFE2L2HDAC2HDAC8CYP3A4 | |
| SCHEMBL9063905 | 0.83 | HDAC2 (0.43) | RELAHDAC2HDAC8NR1H4 | |
| SCHEMBL8965558 | 0.83 | BCL2L1 (0.48) | RELANFE2L2HDAC2HDAC8CYP3A4 | |
| SCHEMBL9063419 | 0.83 | HDAC2 (0.43) | RELAHDAC2HDAC8NR1H4 | |
| SCHEMBL9064292 | 0.80 | HDAC2 (0.43) | HDAC2HDAC8 | |
| SCHEMBL8965199 | 0.78 | NFE2L2 (0.46) | RELANFE2L2HDAC1HDAC6NQO2 | |
| SCHEMBL8965031 | 0.77 | MAPT (0.48) | RELAABL1ABCB1BCRHDAC4 | |
| SCHEMBL28498982 | 0.74 | THRB (0.64) | HDAC4HDAC2HDAC8ERCC5FEN1 | |
| SCHEMBL27684130 | 0.74 | THRB (0.64) | HDAC4HDAC2HDAC8ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696271-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025430-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |