Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244028 | 1.00 | GAA (0.50) | GAALMNAF2CHRNA7TDP1 | |
| SCHEMBL8799724 | 0.90 | GAA (0.45) | GAALMNAF2CHRNA7TDP1 | |
| SCHEMBL8488840 | 0.78 | MAPT (0.42) | GAALMNAF2CHRNA7TDP1 | |
| SCHEMBL8488838 | 0.78 | MAPT (0.42) | GAALMNAF2CHRNA7TDP1 | |
| SCHEMBL8488841 | 0.78 | MAPT (0.42) | GAALMNAF2CHRNA7TDP1 | |
| SCHEMBL1751897 | 0.77 | LMNA (0.48) | GAALMNAF2CHRNA7TDP1 | |
| SCHEMBL636837 | 0.77 | LMNA (0.48) | GAALMNAF2CHRNA7TDP1 | |
| SCHEMBL637664 | 0.77 | LMNA (0.48) | GAALMNAF2CHRNA7TDP1 | |
| SCHEMBL16111315 | 0.76 | IDO1 (0.44) | GAALMNAF2CHRNA7KMT2A | |
| SCHEMBL2239675 | 0.76 | LMNA (0.47) | GAALMNAF2CHRNA7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |