Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PPM1B | O75688 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636837 | 1.00 | LMNA (0.48) | LMNAF2PPM1BTDP1TSHR | |
| SCHEMBL637664 | 1.00 | LMNA (0.48) | LMNAF2PPM1BTDP1TSHR | |
| SCHEMBL8458023 | 0.81 | TDP1 (0.50) | LMNATDP1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5692175 | 0.81 | TDP1 (0.50) | LMNATDP1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2969544 | 0.81 | TDP1 (0.50) | LMNATDP1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL8461105 | 0.80 | PARP1 (0.46) | TDP1TSHRKMT2AMAPTALDH1A1 | |
| SCHEMBL2244028 | 0.77 | GAA (0.50) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL8965206 | 0.77 | GAA (0.50) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL23710673 | 0.76 | MEN1 (0.42) | LMNAF2PPM1BKMT2ACHRNA7 | |
| SCHEMBL9618911 | 0.76 | BCHE (0.48) | KMT2ACHRNA7MAPTMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452258-A | A kind of preparation method of dipeptides valine Boroproline salt | BALMXY PHARMACEUTIC CO LTD | 2019-11-15 | — | — | CN | claimed |
| US-4259383-A | PEROXY COMPOUNDS | STERLING DRUG INC. (US) | 1981-03-31 | — | — | US | claimed |
| US-7968748-B2 | Process for resolving racemic mixtures and a diastereoisomeric complex of a resolving agent and an enantiomer of interest | ABIOGEN PHARMA S.P.A. (IT) | 2011-06-28 | — | — | US | disclosed |
| US-20090292129-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST | ABIOGEN PHARMA S.P.A. (IT) | 2009-11-26 | — | — | US | disclosed |
| EP-1986996-A2 | A PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST | Abiogen Pharma S.p.A. (IT) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007088571-A2 | A PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST | ABIOGEN PHARMA S.P.A. (IT) | 2007-08-09 | — | — | WO | disclosed |
| WO-2006050472-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF 3-AMINOPROPYLPHOSPHONOUS AND -PHOSPHINIC ACIDS | XENOPORT, INC. (US) | 2006-05-11 | — | — | WO | disclosed |
| JP-2003335766-A | METHOD FOR PRODUCING DIBENZOYLTARTARIC ACID AND ACID ANHYDRIDE THEREOF | NIPPON LIGHT METAL CO LTD | 2003-11-28 | — | — | JP | disclosed |
| EP-0600714-B1 | Process for producing O,O'-diacyltartaric anhydride and process for producing O,O'-diacyltartaric acid | TORAY INDUSTRIES (JP) | 1999-08-18 | — | — | EP | disclosed |
| EP-0924188-A1 | Production of 0,0'-diacyltartaric acid crystals | TORAY INDUSTRIES, INC. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | disclosed |
| US-5451687-A | Process for producing O,O'-diacyltartaric anhydride and process for producing O,O'-diacyltartaric acid | TORAY INDUSTRIES, INC. (JP) | 1995-09-19 | — | — | US | disclosed |
| EP-0600714-A1 | Process for producing O,O'-diacyltartaric anhydride and process for producing O,O'-diacyltartaric acid | TORAY INDUSTRIES, INC. (JP) | 1994-06-08 | — | — | EP | disclosed |
| EP-0256586-B1 | PROCESS FOR THE PREPARATION OF ESTERS OF 4-(2,3-EPOXYPROPOXY)PHENYLACETIC ACID AND 4-(2-HYDROXY-3-ISOPROPYLAMINO-PROPOXY)PHENYLACETIC ACID AND/OR ATENOLOL IN STEREOSPECIFIC FORM | GIST-BROCADES N.V. (NL) | 1992-05-13 | — | — | EP | disclosed |
| EP-0256586-A1 | Process for the preparation of esters of 4-(2,3-epoxypropoxy)phenylacetic acid and 4-(2-hydroxy-3-isopropylamino-propoxy)phenylacetic acid and/or atenolol in stereospecific form | GIST-BROCADES N.V. (NL) | 1988-02-24 | — | — | EP | disclosed |
| US-4318819-A | Chiral supports for resolution of racemates | UOP INC. (US) | 1982-03-09 | — | — | US | disclosed |
| US-4318820-A | Chiral supports for resolution of racemates | UOP INC. (US) | 1982-03-09 | — | — | US | disclosed |
| US-4259383-A | PEROXY COMPOUNDS | STERLING DRUG INC. (US) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292129-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST | SRR, EPHX2, ALOX5 | LMNA 715/4885F2 153/4885PPM1B 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.