Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995982 | 0.86 | MEN1 (0.49) | HSP90AA1MEN1KMT2AGAATLR9 | |
| SCHEMBL225820 | 0.85 | GAA (0.58) | MEN1KMT2AGAATLR9PKM | |
| SCHEMBL237914 | 0.83 | GAA (0.44) | MEN1KMT2AGAATLR9PKM | |
| SCHEMBL8995929 | 0.82 | MAPT (0.50) | MEN1KMT2AGAAALDH1A1L3MBTL1 | |
| SCHEMBL8995936 | 0.79 | MEN1 (0.55) | MEN1KMT2AGAAALDH1A1L3MBTL1 | |
| SCHEMBL10189790 | 0.79 | GAA (0.74) | HSP90AA1MEN1KMT2AGFERGAA | |
| SCHEMBL8965241 | 0.76 | HSP90AA1 (0.65) | HSP90AA1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL5837168 | 0.76 | GAA (0.49) | MEN1KMT2AGAATLR9PKM | |
| SCHEMBL4894350 | 0.75 | MEN1 (0.54) | MEN1KMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL2983688 | 0.75 | GAA (0.57) | MEN1KMT2AGAATLR9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537640-B1 | Polymers derived from a conjugated diolefin, a vinyl-substituted aromatic compound, and olefinically unsaturated nitrile | GOODYEAR TIRE & RUBBER (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0570825-B1 | Tire sidewall composition containing silica having low PH | GOODYEAR TIRE & RUBBER (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0475215-B1 | Carboxylic acid esters with thio groups | GOODYEAR TIRE & RUBBER (US) | 1994-10-19 | — | — | EP | disclosed |
| US-5310815-A | Improved wet traction of tire treads without sacrificing wear resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0570825-A1 | Tire sidewall composition containing silica having low PH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5244028-A | Natural rubber or polybutadiene, silica, antidegradation agent, carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5225479-A | Wear resistance, wet traction | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5216049-A | A phenolic or amine stabilizer and an organothioalkylene styrene bound to a polymer; aging resistance; rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0538722-A1 | A process for the production of carboxylated latexes by the selective monomer addition and polymerization | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0537640-A1 | Polymers derived from a conjugated diolefin, a vinyl-substituted aromatic compound, and olefinically unsaturated nitrile | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5171768-A | Continuous processing in four zones; selective addition of conjugated diene to partially polymerized non-carboxylic monomer; butadiene-itaconic acid-butadiene terpolymer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0475215-A1 | Carboxylic acid esters with thio groups | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5069819-A | SYNERGISTS FOR CONVENTIONAL PHENOLIC AND AMINE ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0075529-B1 | IMPROVED CONTINUOUS EMULSION POLYMERIZATION PROCESS OF A DIENE LATEX | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-02-26 | — | — | EP | disclosed |
| US-4559374-A | VINYLIDENE CHLORIDE AND AT LEAST ONE MONO-ETHYLENTICALLY UNSATURATED CARBOXYLIC ACID | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1985-12-17 | — | — | US | disclosed |
| US-4480078-A | MULTIZONAL POLYMERIZATION OF CONJUGATED DIENE, NONCARBOXYLIC COMONOMER, AND MALEIC OR ITACONIC ACID | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0075529-A2 | Improved continuous emulsion polymerization process of a diene latex | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-03-30 | — | — | EP | disclosed |