Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30527786 | 0.93 | ACHE (0.49) | ACE2ACHEBACE1GPR84CA1 | |
| SCHEMBL29177079 | 0.91 | ACHE (0.47) | ACE2ACHEBACE1GPR84CA1 | |
| SCHEMBL8965243 | 0.87 | ACHE (0.55) | ACE2ACHEBACE1GPR84CA1 | |
| SCHEMBL8965248 | 0.87 | ACHE (0.55) | ACE2ACHEBACE1GPR84CA1 | |
| SCHEMBL31511871 | 0.84 | ACE2 (0.41) | ACE2ACHEBACE1GPR84FFAR1 | |
| SCHEMBL31511868 | 0.79 | ACHE (0.60) | ACE2ACHEBACE1GPR84FFAR1 | |
| SCHEMBL900317 | 0.79 | GABRP (0.48) | ACHEBACE1HCAR2GABRPGABRD | |
| SCHEMBL17021602 | 0.79 | GABRP (0.48) | ACHEBACE1HCAR2GABRPGABRD | |
| SCHEMBL900319 | 0.79 | GABRP (0.48) | ACHEBACE1HCAR2GABRPGABRD | |
| SCHEMBL8948047 | 0.78 | CA1 (0.44) | ACE2GPR84CA1FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140073703-A1 | PHYTOL AS A CHOLESTEROL LOWERING AGENT | OLOFSSON PETER (SE) | 2014-03-13 | — | — | US | disclosed |
| EP-2249819-A1 | PHYTOL AS A CHOLESTEROL LOWERING AGENT | Olofsson, Peter (SE) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009113952-A1 | PHYTOL AS A CHOLESTEROL LOWERING AGENT | OLOFSSON PETER (SE) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073703-A1 | PHYTOL AS A CHOLESTEROL LOWERING AGENT | SREBF2, PNLIP, APOL1 | ACE2 758/4885ACHE 692/4885BACE1 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.