Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198208 | 0.80 | ALOX5 (0.61) | ALOX5CYP3A4MMP13 | |
| SCHEMBL8966035 | 0.76 | ALOX5 (0.57) | ALOX5EPHX2 | |
| SCHEMBL1489099 | 0.75 | L3MBTL1 (0.45) | CYP3A4 | |
| SCHEMBL31395062 | 0.68 | GABRG2 (0.65) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20491327 | 0.68 | GABRG2 (0.65) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6215483 | 0.68 | GABRG2 (0.45) | GABRG2GABRB3GABRA5GABRA3ESR2 | |
| SCHEMBL8965561 | 0.67 | BCL2L1 (0.48) | ALOX5CYP17A1CYP3A4ESR2CNR1 | |
| SCHEMBL8965558 | 0.67 | BCL2L1 (0.48) | ALOX5CYP17A1CYP3A4ESR2CNR1 | |
| SCHEMBL8965132 | 0.67 | BCL2L1 (0.48) | ALOX5CYP17A1CYP3A4ESR2CNR1 | |
| SCHEMBL11554410 | 0.67 | ESR2 (0.47) | CYP17A1CYP3A4ESR2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696271-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025430-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |