Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.57 |
| ▸ | PTGIR | P43119 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769715 | 0.79 | PPARA (0.74) | PTGDR2PTGIRPPARAPPARGALOX15 | |
| SCHEMBL8356621 | 0.78 | GPR84 (0.44) | — | |
| SCHEMBL8965343 | 0.77 | PTGDR2 (0.56) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL4271985 | 0.77 | PTGDR2 (0.56) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8804127 | 0.77 | PTGDR2 (0.67) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8965420 | 0.77 | PTGDR2 (0.61) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8965929 | 0.77 | PTGDR2 (0.61) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL2770489 | 0.77 | PPARA (0.62) | PTGDR2PTGIRPPARAPPARGLMNA | |
| SCHEMBL8964950 | 0.76 | PTGDR2 (0.68) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8965375 | 0.76 | PTGDR2 (0.63) | PTGDR2PTGIRPPARAPPARGPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |