SCHEMBL896530

SCHEMBL896530

N#CCCCNc1ccc(C=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.44
ALDH1A1 P00352 2/20 0.44
HTT P42858 1/20 0.40
EGFR P00533 2/20 0.38
HIF1A Q16665 3/20 0.36
EPAS1 Q99814 3/20 0.36
THRB P10828 1/20 0.36
MAPT P10636 1/20 0.35
ALDH1A3 P47895 1/20 0.34
TYR P14679 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
APP P05067 1/20 0.33
PRSS1 P07477 2/20 0.33
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27714466 0.89 ALDH1A1 (0.54) GAAALDH1A1HTTEGFRHIF1A
SCHEMBL8651569 0.77 ALDH1A1 (0.43) ALDH1A1MAPTPRSS1
SCHEMBL5551251 0.77 MAPT (0.59) GAAALDH1A1HTTTHRBMAPT
SCHEMBL7100388 0.77 GAA (0.47) GAAALDH1A1HTTTHRBMAPT
SCHEMBL5493605 0.77 LMNA (0.43) GAAALDH1A1MAPTALDH1A3CA2
SCHEMBL5506124 0.76 ALDH1A1 (0.64) GAAALDH1A1HTTTHRBMAPT
SCHEMBL5504318 0.76 GAA (0.46) GAAALDH1A1HTTTHRBMAPT
SCHEMBL5543098 0.75 ABL1 (0.45) GAAALDH1A1ALDH1A3PRSS1CYP2A6
SCHEMBL12451481 0.75 PRSS1 (0.42) ALDH1A1MAPTCA2CA9APP
SCHEMBL10063731 0.74 ALDH1A1 (0.49) GAAALDH1A1MAPTPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12235217-B2 Diagnostic test kits for sample preparation and analysis SCANWELL HEALTH, INC. (US) 2025-02-25 US claimed
US-20250258104-A1 DIAGNOSTIC TEST KITS FOR SAMPLE PREPARATION AND ANALYSIS SCANWELL HEALTH INC (US) 2025-08-14 US disclosed
US-12235217-B2 Diagnostic test kits for sample preparation and analysis SCANWELL HEALTH, INC. (US) 2025-02-25 US disclosed
US-9556187-B2 Substituted pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidines and JAK inhibitors comprising the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-01-31 US disclosed
EP-3112370-A1 TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS Nissan Chemical Industries, Ltd. (JP) 2017-01-04 EP disclosed
US-20160102102-A1 TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-04-14 US disclosed
US-9216999-B2 Substituted pyrrolo[2,3-h][1,6]naphthyridines and compositions thereof as JAK inhibitors NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-22 US disclosed
US-9164376-B2 Patterning nano-scale patterns on a film comprising unzipping copolymers GLOBALFOUNDRIES INC. (KY) 2015-10-20 US disclosed
EP-2742049-A1 TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS Nissan Chemical Industries, Ltd. (JP) 2014-06-18 EP disclosed
US-8574815-B2 Patterning nano-scale patterns on a film comprising unzipping copolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-11-05 US disclosed
WO-2013024895-A1 TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-02-21 WO disclosed
US-20120301672-A1 PATTERNING NANO-SCALE PATTERNS ON A FILM COMPRISING UNZIPPING COPOLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-11-29 US disclosed
US-20120297905-A1 PATTERNING NANO-SCALE PATTERNS ON A FILM COMPRISING UNZIPPING COPOLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-11-29 US disclosed
US-20120082944-A1 Patterning nano-scale patterns on a film comprising unzipping copolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-04-05 US disclosed
US-4540790-A COLORFORMERS INC PRESSURE SENSITIVE CARBONLESS DUPLICATION THE HILTON-DAVIS CHEMICAL CO. (US) 1985-09-10 US disclosed
EP-0061128-B1 PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND SYSTEMS CONTAINING THEM STERLING DRUG INC. (US) 1985-09-04 EP disclosed
US-4446321-A COLOR FORMERS, CARBON-FREE DUPLICATION STERLING DRUG INC. (US) 1984-05-01 US disclosed
US-4396767-A COLORS, CARBONLESS DUPLICATION STERLING DRUG INC. (US) 1983-08-02 US disclosed
US-4363503-A FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS STERLING DRUG INC. (US) 1982-12-14 US disclosed
EP-0061128-A1 Pyridine compounds, process for their preparation and systems containing them STERLING DRUG INC. (US) 1982-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160102102-A1 TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS JAK2, JAK1, JAK3 GAA 3189/4885ALDH1A1 3086/4885HTT 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.