SCHEMBL8965320

SCHEMBL8965320

COc1nc(Cl)c(OC(=O)O)s1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965355 0.86 PRNP (0.32) TSHR
SCHEMBL8965387 0.79 ALDH1A1 (0.42) ALDH1A1HPGDTSHR
SCHEMBL8964648 0.77 PTGDR2 (0.37) ALDH1A1HPGDTSHR
SCHEMBL8965318 0.76 ALDH1A1 (0.44) ALDH1A1HPGDTSHR
SCHEMBL9196575 0.69 ALDH1A1 (0.35) ALDH1A1HPGD
SCHEMBL3271932 0.65 MEN1 (0.53) ALDH1A1
SCHEMBL5238525 0.65 TPMT (0.35) ALDH1A1HPGD
SCHEMBL3252712 0.64 LMNA (0.38) ALDH1A1HPGD
SCHEMBL3841963 0.63
SCHEMBL20549146 0.62 PLK1 (0.34) ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459244-B1 Sulphonilised carboxylic acid amides BAYER AG (DE) 1996-02-28 EP disclosed
EP-0569810-A1 Sulphonylamide herbicides BAYER AG (DE) 1993-11-18 EP disclosed
EP-0459244-A1 Sulphonilised carboxylic acid amides BAYER AG (DE) 1991-12-04 EP disclosed