Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | XPO1 | O14980 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL911369 | 0.85 | CYP1A2 (0.46) | PDE3BPDE3ABACE1CYP1A2CYP2A6 | |
| SCHEMBL926949 | 0.81 | PDE3B (0.45) | PDE3BPDE3ABACE1CYP1A2CYP2A6 | |
| SCHEMBL928218 | 0.79 | NPC1 (0.43) | PDE3BPDE3ABACE1CYP1A2CYP2A6 | |
| Toluene SCHEMBL28383748 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP2A6NPC1RAB9ACYP11B1 | |
| SCHEMBL30129541 | 0.74 | NCF1 (0.46) | PDE3BPDE3ACYP1A2EGFRNPC1 | |
| SCHEMBL28609417 | 0.74 | NCF1 (0.46) | PDE3BPDE3ACYP1A2EGFRNPC1 | |
| SCHEMBL443070 | 0.71 | CYP1A2 (0.79) | CYP1A2CYP2A6CA2NPC1RAB9A | |
| SCHEMBL29447161 | 0.71 | CYP1A2 (0.79) | CYP1A2CYP2A6CA2NPC1RAB9A | |
| SCHEMBL1145044 | 0.70 | HTT (0.48) | CA2NPC1RAB9ACYP11B1CYP11B2 | |
| SCHEMBL7378448 | 0.69 | TRPM5 (0.40) | TRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530136-B1 | Nematicidal agents | CIBA GEIGY AG (CH) | 1996-02-21 | — | — | EP | claimed |
| EP-0530136-A2 | Nematicidal agents | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | claimed |
| US-20220213086-A1 | AZOLE COMPOUNDS AS IRAK INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. | 2022-07-07 | — | — | US | disclosed |
| EP-0530136-B1 | Nematicidal agents | CIBA GEIGY AG (CH) | 1996-02-21 | — | — | EP | disclosed |
| US-5451595-A | Benzoisothiazole ethers | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0530136-A2 | Nematicidal agents | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213086-A1 | AZOLE COMPOUNDS AS IRAK INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | IRAK2, IRAK4, IRAK3 | PDE3B 1557/4885PDE3A 1711/4885TRPM5 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.