Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ciaftalan SCHEMBL5973010 | 0.91 | PDE5A (0.40) | PDE5APDE4APDE4BPDE4CPDE4D | |
| Ciaftalan SCHEMBL11520284 | 0.84 | MEN1 (0.39) | KDM4ELMNAHTTSMN1; SMN2CYP1A2 | |
| Ciaftalan SCHEMBL11414517 | 0.81 | PDE5A (0.39) | PDE5APDE4APDE4BPDE4CPDE4D | |
| Ciaftalan SCHEMBL9075585 | 0.79 | ELANE (0.36) | PDE5APDE4APDE4BPDE4CPDE4D | |
| Ciaftalan SCHEMBL7950273 | 0.79 | HPGD (0.39) | PDE5ALMNAALDH1A1TSHRHSD17B10 | |
| Ciaftalan SCHEMBL9471480 | 0.79 | ELANE (0.33) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5707000 | 0.79 | PDE5A (0.45) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28034499 | 0.79 | PDE5A (0.46) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28035087 | 0.79 | PDE5A (0.46) | PDE5APDE4APDE4BPDE4CPDE4D | |
| Ciaftalan SCHEMBL29211555 | 0.78 | TLR8 (0.44) | ALDH1A1TSHRELANETLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549068-B1 | Alkyl peroxides and uses | DSM NV (NL) | 1996-02-21 | — | — | EP | disclosed |