⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486686 | 0.85 | LMNA (0.39) | — | |
| SCHEMBL394477 | 0.76 | — | — | |
| SCHEMBL3575455 | 0.74 | — | — | |
| SCHEMBL6972906 | 0.74 | — | — | |
| SCHEMBL3381566 | 0.74 | — | — | |
| SCHEMBL3381842 | 0.70 | GAA (0.40) | — | |
| SCHEMBL10617694 | 0.70 | PKM (0.31) | — | |
| SCHEMBL10969186 | 0.68 | CYP1A2 (0.36) | — | |
| SCHEMBL6298021 | 0.67 | ALDH1A1 (0.34) | — | |
| SCHEMBL8474795 | 0.65 | RECQL (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11528907-B2 | Heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-20 | — | — | US | claimed |
| US-20210386070-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-16 | — | — | US | claimed |
| US-RE48841-E1 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-07 | — | — | US | claimed |
| US-11059828-B2 | Disubstituted octahydropyrrolo[3,4-C]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2021-07-13 | — | — | US | claimed |
| EP-3784661-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-03-03 | — | — | EP | claimed |
| CN-112204021-A | Novel heteroaryltriazole and heteroaryltetrazole compounds as pesticides | 拜耳公司 | 2021-01-08 | — | — | CN | claimed |
| US-20200048263-A1 | Disubstituted Octahydropyrrolo[3,4-C]Pyrroles As Orexin Receptor Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-13 | — | — | US | claimed |
| EP-3093291-B1 | DISUBSTITUTED OCTAHY - DROPYRROLO [3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-05-08 | — | — | EP | claimed |
| US-20170129901-A1 | Disubstituted Octahydropyrrolo[3,4-C]Pyrroles As Orexin Receptor Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2017-05-11 | — | — | US | claimed |
| EP-3093291-A1 | DISUBSTITUTED OCTAHY - DROPYRROLO [3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2016-11-16 | — | — | EP | claimed |
| US-20050245547-A1 | 6-((6,7-Bis(methoxy)-4-quinolinyl)oxy)-N-(3-methylphenyl)-1-benzofuran-3-carboxamide;antiproliferative; -metastasis; -carcinogenic; -tumor; -inflammatory; -arthritic agents;hypotensive agents; myocardium necrosis; rheumatic diseases; tyrosine kinase inhibitors; antiallergens; asthma | AMGEN INC. | 2005-11-03 | — | — | US | claimed |
| WO-2005073224-A2 | QUINOLINE QUINAZOLINE PYRIDINE AND PYRIMIDINE COUNDS AND THEIR USE IN THE TREATMENT OF INFLAMMATION ANGIOGENESIS AND CANCER | AMGEN INC (US) | 2005-08-11 | — | — | WO | claimed |
| WO-2005070891-A2 | COMPOUNDS AND METHODS OF USE | AMGEN INC (US) | 2005-08-04 | — | — | WO | claimed |
| US-6143694-A | AIDING RIPENING OF TOBACCO PLANT BY PREHARVEST APPLICATION OF NON-PHYTOTOXIC AMOUNT OF 2-(4,5-DIHYDRO-4-METHYL-4-(1-METHYLETHYL)-5-OXO-1H-IMIDAZOL-2 -YL)ARYLCARBOXYLATE | TAYLOR JOHN B (US) | 2000-11-07 | — | — | US | claimed |
| US-4889553-A | Herbicides | SCHERING AGROCHEMICALS (GB) | 1989-12-26 | — | — | US | claimed |
| EP-0132230-B1 | PROCESS FOR THE PREPARATION OF SULFONYL UREA | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | claimed |
| EP-0246749-A2 | Triazole herbicides | AgrEvo UK Limited (GB) | 1987-11-25 | — | — | EP | claimed |
| US-4656273-A | Process for producing sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1987-04-07 | — | — | US | claimed |
| EP-0173313-A2 | Heteroaryl thioureas | BAYER AG (DE) | 1986-03-05 | — | — | EP | claimed |
| EP-0132230-A2 | Process for the preparation of sulfonyl urea | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | claimed |