SCHEMBL8965744

SCHEMBL8965744

CCCCC(CC)C[N+]1(Cc2ccccc2)CCOCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 1/20 0.37
CA2 P00918 1/20 0.35
CYP3A4 P08684 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
APOBEC3A P31941 2/20 0.34
APOBEC3G Q9HC16 2/20 0.34
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CNR2 P34972 1/20 0.33
CYP2D6 P10635 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
LMNA P02545 2/20 0.33
CTSS P25774 1/20 0.32
MAPK1 P28482 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8059280 0.88 ALDH1A1 (0.38) ALDH1A1KDM4ECA2CYP3A4MEN1
SCHEMBL20657998 0.82 ALDH1A1 (0.44) ALDH1A1KDM4ECA2CYP3A4MEN1
SCHEMBL21694862 0.81 ALDH1A1 (0.42) ALDH1A1CA2CYP3A4MEN1KMT2A
SCHEMBL8965317 0.80 APOBEC3A (0.36) ALDH1A1MEN1KMT2AAPOBEC3AAPOBEC3G
SCHEMBL7723410 0.77 DNM1 (0.37) MEN1KMT2AAPOBEC3AAPOBEC3GCYP2D6
SCHEMBL8053841 0.77 DNM1 (0.37) MEN1KMT2AAPOBEC3AAPOBEC3GCYP2D6
SCHEMBL6122174 0.76 SMN1; SMN2 (0.36) ALDH1A1KDM4EMEN1KMT2ANPC1
Bromide SCHEMBL9784512 0.76 DNM1 (0.39) ALDH1A1MEN1KMT2AAPOBEC3AAPOBEC3G
Ammonia Solution, Strong SCHEMBL8092892 0.76 DNM1 (0.36) MEN1KMT2AAPOBEC3AAPOBEC3GCYP2D6
Hydrochloric Acid SCHEMBL6939665 0.76 MEN1 (0.39) MEN1KMT2AAPOBEC3AAPOBEC3GCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0619300-B1 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF AG (DE) 1996-12-27 EP disclosed
US-5510528-A Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
US-5446199-A Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed
EP-0619300-A2 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF Aktiengesellschaft (DE) 1994-10-12 EP disclosed