SCHEMBL8965317

SCHEMBL8965317

CCCC[N+]1(Cc2ccccc2)CCOCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 4/20 0.36
APOBEC3G Q9HC16 4/20 0.36
CYP2D6 P10635 2/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
SIGMAR1 Q99720 2/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
KCNH2 Q12809 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PLA2G1B P04054 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
CHRNA7 P36544 2/20 0.33
RGS12 O14924 1/20 0.33
HTT P42858 1/20 0.33
CHRNB2 P17787 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7723410 0.94 DNM1 (0.37) APOBEC3AAPOBEC3GCYP2D6CTDSP1SIGMAR1
SCHEMBL8053841 0.94 DNM1 (0.37) APOBEC3AAPOBEC3GCYP2D6CTDSP1SIGMAR1
Bromide SCHEMBL9784512 0.92 DNM1 (0.39) APOBEC3AAPOBEC3GCYP2D6CTDSP1SIGMAR1
Ammonia Solution, Strong SCHEMBL8092892 0.92 DNM1 (0.36) APOBEC3AAPOBEC3GCYP2D6CTDSP1SIGMAR1
Hydrochloric Acid SCHEMBL6939665 0.92 MEN1 (0.39) APOBEC3AAPOBEC3GCYP2D6CTDSP1SIGMAR1
SCHEMBL6122174 0.90 SMN1; SMN2 (0.36) APOBEC3AAPOBEC3GCYP2D6CTDSP1SIGMAR1
Hydrochloric Acid SCHEMBL6935021 0.90 MEN1 (0.37) APOBEC3AAPOBEC3GCYP2D6CTDSP1SIGMAR1
SCHEMBL23817608 0.86 LTA4H (0.46) APOBEC3AAPOBEC3GCYP2D6CTDSP1SIGMAR1
SCHEMBL5289149 0.85 CYP2D6 (0.40) APOBEC3AAPOBEC3GCYP2D6SIGMAR1SMN1; SMN2
SCHEMBL6122277 0.84 MAOA (0.39) APOBEC3AAPOBEC3GCYP2D6CTDSP1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0619300-B1 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF AG (DE) 1996-12-27 EP disclosed
US-5510528-A Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
US-5446199-A Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed
EP-0619300-A2 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF Aktiengesellschaft (DE) 1994-10-12 EP disclosed