SCHEMBL8965764

SCHEMBL8965764

C=COC(=O)C(=C)C.C=COC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
HSD17B10 Q99714 1/20 0.35
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL9448802 0.94 ALDH1A1 (0.39) ALDH1A1TSHRTDP1HSD17B10THRB
SCHEMBL35971 0.93
Acrylic Acid SCHEMBL28786340 0.92 LMNA (0.40) ALDH1A1TSHRTDP1HSD17B10
SCHEMBL11590228 0.90
SCHEMBL11256472 0.90
SCHEMBL11854992 0.90
SCHEMBL28402005 0.88 ALDH1A1 (0.42) ALDH1A1TSHRTDP1HSD17B10THRB
Butadiene SCHEMBL5595802 0.88 ALDH1A1 (0.46) ALDH1A1TSHRTDP1HSD17B10THRB
Bicarbonate SCHEMBL28402036 0.88 ALDH1A1 (0.46) ALDH1A1TSHRTDP1HSD17B10THRB
Hydrochloric Acid SCHEMBL28368190 0.88 ALDH1A1 (0.46) ALDH1A1TSHRTDP1HSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5540837-A CHARGED POLYELECTROLYTES BUERGER WOLFGANG DR (DE) 1996-07-30 US disclosed
EP-0513331-A1 AZEOTROPIC ASSISTED TRANSVINYLATION TECHNOLOGY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-11-19 EP disclosed
WO-1992009554-A1 AZEOTROPIC ASSISTED TRANSVINYLATION TECHNOLOGY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-06-11 WO disclosed