Methacrylic Acid

Methacrylic Acid

SCHEMBL9448802

C=C(C)C(=O)O.C=COC(=O)C(=C)C.C=COC(C)=O

nearest known ligand 0.39

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965764 0.94 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10TDP1THRB
Methacrylic Acid SCHEMBL5356962 0.94 ALDH1A1 (0.44) ALDH1A1TSHRTDP1THRB
Methacrylic Acid SCHEMBL307309 0.91 TDP1 (0.36) ALDH1A1TSHRHSD17B10TDP1
Acrylic Acid SCHEMBL28786340 0.90 LMNA (0.40) ALDH1A1TSHRHSD17B10TDP1
Methacrylic Acid SCHEMBL27704543 0.89 TDP1 (0.35) ALDH1A1HSD17B10TDP1
Methacrylic Acid SCHEMBL3643411 0.89 TDP1 (0.35) ALDH1A1HSD17B10TDP1
Methacrylic Acid SCHEMBL28330824 0.88 ALDH1A1 (0.58) ALDH1A1TSHR
Methacrylic Acid SCHEMBL11227746 0.88 LMNA (0.42) ALDH1A1TSHRHSD17B10THRB
Methacrylic Acid SCHEMBL28124339 0.87 TDP1 (0.33) ALDH1A1HSD17B10TDP1
Bicarbonate SCHEMBL28402036 0.87 ALDH1A1 (0.46) ALDH1A1TSHRHSD17B10TDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210207-A Forming vinyl ethers, esters and amides, ruthenium catalyst UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-05-11 US disclosed
US-4981973-A BRONSTED ACID, RUTHENIUM CATALYST UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1991-01-01 US disclosed