Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MYB | P10242 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558928 | 0.90 | ESR1 (0.42) | ESR1ESR2NPSR1KDM4EMAPK1 | |
| SCHEMBL8965886 | 0.80 | PTPN1 (0.44) | ESR1ESR2NPSR1MEN1KMT2A | |
| SCHEMBL8965880 | 0.80 | MEN1 (0.46) | ESR1ESR2KDM4EMTNR1AMEN1 | |
| SCHEMBL8966375 | 0.78 | ESR1 (0.46) | ESR1ESR2NPSR1KDM4EMAPK1 | |
| SCHEMBL17765400 | 0.78 | TP53 (0.44) | ESR1ESR2NPSR1MYBHTR2A | |
| SCHEMBL8970603 | 0.77 | ESR1 (0.42) | ESR1ESR2NPSR1KDM4EMAPK1 | |
| SCHEMBL8966126 | 0.77 | ESR1 (0.66) | ESR1ESR2HTT | |
| SCHEMBL8966242 | 0.76 | ESR1 (0.68) | ESR1ESR2HTT | |
| SCHEMBL8965793 | 0.76 | ESR1 (0.68) | ESR1ESR2HTT | |
| SCHEMBL8966583 | 0.73 | THRA (0.43) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524742-B1 | Benzo(a)fluorene compounds | LILLY CO ELI (US) | 1996-02-28 | — | — | EP | disclosed |